Monro-Kellie hypothesis
From IDWiki
Definition
- Pressure-volume relationship between ICP, volume of CSF, blood, and brain tissue, and cerebral perfusion pressure
- Fixed cranial vault with three compartments
- Brain parenchyma
- Cerebrospinal fluid (CSF)
- Vasculature
- Venous
- Arterial
- Compensation between the compartments can occur, up to a point
- Autoregulation of blood vessel constriction/dilatation
- Ventricles, which can compress the brain parenchyma