Membranous nephropathy
From IDWiki
Etiology
- Primary/idiopathic
- Cancer (non-Hodgkin lymphoma and solid tumours)
- Drugs (gold and penicillamine)
- Infections (malaria, HBV, HCV)
- Lupus
Management
Non-immunosuppressive
- ACEi/ARB
- Statin
- Thromboprophylaxis (high risk)
Immunosuppressive
Low risk
- No need for immunosuppressing medications
Moderate risk
- Prednisone with cyclophosphamide
- Alternatives include cyclosporine/tacrolimus with prednisone
- Second-line is rituximab
