Model for end-stage liver disease

From IDWiki
(Redirected from MELD)

Background

  • Used to predict mortality from cirrhosis
  • An online calculator is available at MDCalc

Criteria

  • Dialysis at least twice in the past week, or CVVHD for at least 24 hours in the past week
  • Creatinine
  • Bilirubin
  • INR
  • Sodium

Interpretation

  • Calculates a score using a formula
    • MELD = (0.957 * ln(Creat) + 0.378 * ln(Bilirubin) + 1.120 * ln(INR) + 0.643 ) * 10
      • All values are in US units
      • If hemodialysis, value for Creatinine is automatically set to 353.6 umol/L (4 mg/dl)
    • MELD-Na = MELD - Na - 0.025*(MELD)*(140-Na) + 140
MELD-Na 90-day Mortality
<17 <2%
17 to 20 3 to 4%
21 to 22 7 to 10%
23 to 26 14 to 15%
27 to 31 27 to 32%
≥32 65 to 66%