Lille score
From IDWiki
Background
- Scoring system for alcoholic hepatitis
- Done at day 7 of steroids in order to predict whether there will be any improvement from extending the course further
- Available at MD Calc
Calculation
- Components: age, albumin, bilirubin (initial), bilirubin (day 7), creatinine, and PT
- Formula
- R = 3.19 – 0.101*(age, years) + 0.147*(albumin day 0, g/L) + 0.0165* (evolution in bilirubin level, µmol/L) - 0.206*(renal insufficiency) - 0.0065*(bilirubin day 0, µmol/L) - 0.0096*(PT, sec) Renal insufficiency = 1 (if Cr >1.3 mg/dL (115 µmol/L)) or 0 (if ≤1.3 mg/dL (115 µmol/L))
- Lille Model Score = (exp(-R))/(1 + exp(-R))
Interpretation
- Scores >0.45 predict a 6-month survival of 25%.
- Scores <0.45 predict a 6-month survival of 85%.
