Imiquimod

From IDWiki

Background

  • TLR7 ± TLR8 agonist
  • Used to treat anogenital warts

Dosing

  • 5% cream applied topically nightly every Monday, Wednesday, and Friday, then washed off after 6 to 10 hours, continued to resolution of lesions
  • 3.75% cream applied topically nightly, then washed off after 8 hours, continued for up to 8 weeks

Safety

Adverse Drug Reactions

  • Cutaneous drug reactions are common, with itching, burning, erythema, erosions, and edema
    • More common with 5% than 3.75%
    • Must be washed off after 6 to 10 hours