High dose ARA-C
From IDWiki
Definition
- High-dose cytarabine at 1,000-3,000 mg/m2 IV over 1-3 hours every 12 hours for 6 to 12 doses
Indications
- Consolidation of AML and ALL
Side Effects
- Cerebellar toxicity (ataxia)
- Granulocytopenia, thrombocytopenia, leukopenia
- GI disturbances, stomatitis, conjunctivitis, pneumonitis, fever, and dermatitis, palmar-plantar erythrodysesthesia
