Efalizumab

From IDWiki
  • CD 11a inhibitor
  • Monoclonal IgG1 antibody against the α subunit (CD 11a) of LFA-1
    • Affects T cell activation, transfer from circulation to sites of inflammation in the skin, and T cell reactivation in the skin
  • Indications include psoriasis
  • Infectious complications include upper respiratory tract infections, gastroenteritis, and HSV