Cronobacter sakazakii
From IDWiki
Cronobacter sakazakii
Background
Microbiology
- Facultatively anaerobic, oxidase-negative, catalase-positive Gram-negative bacillus within the Enterobacterales
- Previously known as Enterobacter sakazakii
Epidemiology
- Outbreaks have been associated with contaminated infant formula
Clinical Manifestations
- A rare cause of sepsis in infants who are fed infant formula that has not been appropriately heated
Management
- No natural beta-lactamases or resistance to cephalosporins in wild-type isolates
- Intrinsic resistance to lincosamides, glycopeptides, streptogramins, and fusidic acid
- Reasonable to treat infant sepsis with broad-spectrum antibiotics until susceptibilities are available
Prevention
- Appropriate heating of infant formula and cleaning of bottles before using the formula for children below 3 months of age
Further Reading
- Cronobacter: an emerging opportunistic pathogen associated with neonatal meningitis, sepsis and necrotizing enterocolitis. J Perinatol. 2013;33:581-585. doi: 10.1038/jp.2013.26