Cronobacter sakazakii

From IDWiki
Cronobacter sakazakii


Background

Microbiology

  • Facultatively anaerobic, oxidase-negative, catalase-positive Gram-negative bacillus within the Enterobacterales
  • Previously known as Enterobacter sakazakii

Epidemiology

  • Outbreaks have been associated with contaminated infant formula

Clinical Manifestations

  • A rare cause of sepsis in infants who are fed infant formula that has not been appropriately heated

Management

  • No natural beta-lactamases or resistance to cephalosporins in wild-type isolates
  • Intrinsic resistance to lincosamides, glycopeptides, streptogramins, and fusidic acid
  • Reasonable to treat infant sepsis with broad-spectrum antibiotics until susceptibilities are available

Prevention

  • Appropriate heating of infant formula and cleaning of bottles before using the formula for children below 3 months of age

Further Reading

  • Cronobacter: an emerging opportunistic pathogen associated with neonatal meningitis, sepsis and necrotizing enterocolitis. J Perinatol. 2013;33:581-585. doi: 10.1038/jp.2013.26