Congenital HSV
From IDWiki
Background
Clinical Manifestations
- Characterized by microcephaly, hydrocephalus, chorioretinitis, and skin findings
- Rash may be vesicular, bullous, or cicatricial
- Rash either present at birth or within a few days
- Two thirds have severe CNS involvement
Diagnosis
- Most commonly made with PCR of lesions or CSF
- Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process