Conditioning regimens for HSCT

From IDWiki
Regimen Drugs Comments
Myeloablative regimens
BEAM Carmustine, etoposide, cytosine arabinoside, and melphalan Commonly used for non-Hodgkin and Hodgkin lymphoma
Cy/TBI Cyclophosphamide and TBI
Bu4/Cy Busulfan and cyclophosphamide
Flu/Bu4 Busulfan and fludarabine for four days
High-dose melphalan Melphalan Used in preparation for autoHSCT in myeloma
CBV Carmustine once followed by etoposide and cyclophosphamide for four days
Reduced-intensity regimens
Flu/Mel Fludarabine and melphalan
Flu/Bu2 and Flu/Bu3 Fludarabine and busulfan
Flu/Cy Fludarabine and cyclophosphamide
Flu/Bu3/TT Fludarabine, busulfan, and thiotepa
Non-myeloablative regimens
Flu/TBI Fludarabine and TBI
TLI/ATG Total lymphoid irradiation and anti-thymocyte globulin
Low dose TBI TBI

TBI = total body irradiation