Bevacizumab

From IDWiki
(Redirected from Avastin)
  • Recombinant humanized IgG1 anti-VEGF monoclonal antibody
  • Indications include advanced colorectal cancer, non-small cell lung cancer, breast cancer, and renal cancer
    • May be used as an intravitreal injection for macular degeneration
  • Black-box warning for intestinal perforation
  • Infectious complications include intra-abdominal infection, febrile neutropenia, pneumonitis, and possibly also Bacteroides fragilis liver abscess and Fusarium-associated nasal septal perforation